Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vitamin K epoxide reductase complex subunit 1 (Homo sapiens (Human)) | BDBM50535485 (CHEMBL4594145) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Queensland Curated by ChEMBL | Assay Description Inhibition of VKOR (unknown origin) in HEK293 expressing FIXgla-PC incubated for 48 hrs by ELISA | Bioorg Med Chem Lett 29: 1954-1956 (2019) Article DOI: 10.1016/j.bmcl.2019.05.039 BindingDB Entry DOI: 10.7270/Q2TQ652J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin K epoxide reductase complex subunit 1 (Homo sapiens (Human)) | BDBM50343352 (2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Queensland Curated by ChEMBL | Assay Description Inhibition of VKOR (unknown origin) in HEK293 expressing FIXgla-PC incubated for 48 hrs by ELISA | Bioorg Med Chem Lett 29: 1954-1956 (2019) Article DOI: 10.1016/j.bmcl.2019.05.039 BindingDB Entry DOI: 10.7270/Q2TQ652J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin K epoxide reductase complex subunit 1 (Bos taurus) | BDBM50166637 (2'-Biphenyl-4-yl-4-hydroxy-3',4'-dihydro-2'H-[3,4'...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Tunghai University Curated by ChEMBL | Assay Description Inhibitory concentration against beef liver Vitamin K epoxide reductase (vitamin K 2,3-epoxide reductase) | Bioorg Med Chem Lett 15: 2665-8 (2005) Article DOI: 10.1016/j.bmcl.2005.03.005 BindingDB Entry DOI: 10.7270/Q2K073S3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin K epoxide reductase complex subunit 1 (Homo sapiens (Human)) | BDBM50535487 (CHEMBL4530669) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Queensland Curated by ChEMBL | Assay Description Inhibition of VKOR (unknown origin) in HEK293 expressing FIXgla-PC incubated for 48 hrs by ELISA | Bioorg Med Chem Lett 29: 1954-1956 (2019) Article DOI: 10.1016/j.bmcl.2019.05.039 BindingDB Entry DOI: 10.7270/Q2TQ652J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin K epoxide reductase complex subunit 1 (Homo sapiens (Human)) | BDBM50535484 (CHEMBL4517532) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Queensland Curated by ChEMBL | Assay Description Inhibition of VKOR (unknown origin) in HEK293 expressing FIXgla-PC incubated for 48 hrs by ELISA | Bioorg Med Chem Lett 29: 1954-1956 (2019) Article DOI: 10.1016/j.bmcl.2019.05.039 BindingDB Entry DOI: 10.7270/Q2TQ652J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin K epoxide reductase complex subunit 1 (Homo sapiens (Human)) | BDBM50535488 (CHEMBL4443961) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Queensland Curated by ChEMBL | Assay Description Inhibition of VKOR (unknown origin) in HEK293 expressing FIXgla-PC incubated for 48 hrs by ELISA | Bioorg Med Chem Lett 29: 1954-1956 (2019) Article DOI: 10.1016/j.bmcl.2019.05.039 BindingDB Entry DOI: 10.7270/Q2TQ652J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin K epoxide reductase complex subunit 1 (Bos taurus) | BDBM50166638 (13-(4-phenylphenyl)-4,12,14-trioxapentacyclo[11.7....) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tunghai University Curated by ChEMBL | Assay Description Inhibitory concentration against beef liver Vitamin K epoxide reductase (vitamin K 2,3-epoxide reductase) | Bioorg Med Chem Lett 15: 2665-8 (2005) Article DOI: 10.1016/j.bmcl.2005.03.005 BindingDB Entry DOI: 10.7270/Q2K073S3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin K epoxide reductase complex subunit 1 (Homo sapiens (Human)) | BDBM50535486 (CHEMBL4463800) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Queensland Curated by ChEMBL | Assay Description Inhibition of VKOR (unknown origin) in HEK293 expressing FIXgla-PC incubated for 48 hrs by ELISA | Bioorg Med Chem Lett 29: 1954-1956 (2019) Article DOI: 10.1016/j.bmcl.2019.05.039 BindingDB Entry DOI: 10.7270/Q2TQ652J | |||||||||||
More data for this Ligand-Target Pair |